Senior Scientist

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Job Description

We are looking for a highly motivated individual to join the Development Chemistry Team as a Senior Development Scientist.

The Details...

Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and a commercial presence in many global locations across the US, APAC and Europe.

Oxford Nanopore employs from multiple subject areas including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market.

Oxford Nanopore's sequencing platform is the only technology that offers real-time analysis, in fully scalable formats from pocket to population scale, that can analyse native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths. Our goal is to enable the analysis of any living thing, by anyone, anywhere!

We are looking for a highly motivated individual to join the Development Chemistry Team as a Senior Development Scientist.

The Chemistry Development team is responsible for taking complex biomolecule components, central to the sequencing technology, from early development through to product stage. The candidate will use a range of analytical and purification techniques, in combination with their knowledge of chemical biology, to improve and make product-ready these biological components. The candidate, therefore, will play a central role in delivering technology improvements to customer hands in the fastest and best possible way.

Responsibilities include:

• Leading the development of protein nanopores, sequencing components and adapters.
• Purification development on a wide range of biomolecules, primarily using HPLC.
• Bio-characterisation using a wide array of techniques to guide development activities.
• Improving biological components through their design and assembly to increase sequencing accuracy and throughput.
• Bio-conjugation and chemical biology on proteins, peptides and oligonucleotides.
• Technology transfer to both internal and external manufacturing teams.
• Process development and scale up.
• Preparing clearly articulated progress reports and maintaining well-organised records.
• Managing multiple projects in a very fast paced and agile environment.
• Maintaining a safe working environment for all team members and a culture of continuous improvement for health & safety.

What We're Looking For...

• MSc or PhD degree in a physical/life sciences or equivalent experience.
• 4+ years experience in pharmaceutical, biotech/biomedical industry.
• Practical experience in biomolecule chromatography.
• Experience in HPLC and other high resolution characterisation techniques.
• Strong problem solving and analytical skills.
• Strong attention to detail and a high level of organisation.
• Strong communication skills and a desire to learn and build on the role.
• Ability to effectively work on and manage many priorities at one time
• Strong organization skills, including ability to rapidly balance priorities in a fast-pace and multi-tasking environment.
• Working and communicating effectively across a number of research, development and manufacturing groups.
• Highly motivated, self-driven, critical thinking, and strong problem-solving skills.
• Has an approachable manner that encourages interaction with others
• Highly driven with a strong motivation to succeed

Experience in the following areas would be advantageous:

• Proficient with and in-depth understanding of chromatographic equipment, FLPC, HPLC, CE or LC-MS.
• In depth biological macromolecule / protein analytical and biophysical characterisation.
• Experience in bioconjugation and modification of proteins, peptides and oligonucleotide.
• Development and technology transfer experience
• Experience with ONT sequencing kits and platforms
• Experience managing a laboratory and technically leading a team of scientists.

Training will be given and, as such, a willingness to learn and develop is essential.

Applications are encouraged from highly motivated individuals who enjoy taking on new challenges, are quickly adaptable in an exciting and fast-paced environment, and who perform well under pressure.

We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary. Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment.

If you are looking to utilise your skills to really make a difference to humankind, then consider joining our team and apply today!

Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job.

About Us

Oxford Nanopore's goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology enabling the real-time, high-performance, accessible and scalable analysis of DNA and RNA. The technology is used in more than 100 countries to understand the biology of humans and diseases, plants, animals, bacteria, viruses and whole environments.

Oxford Nanopore was founded in 2005 as a spin-out from the University of Oxford and now employs over 1000 employees around the world.

#LI-JC1

About Us

Oxford Nanopore's goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology enabling the real-time, high-performance, accessible and scalable analysis of DNA and RNA. The technology is used in more than 100 countries to understand the biology of humans and diseases, plants, animals, bacteria, viruses and whole environments.

Oxford Nanopore was founded in 2005 as a spin-out from the University of Oxford and now employs over 1000 employees around the world.