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Senior Lab Scientist

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Job Purpose

We're looking for an experienced LBA technician to provide short-term technical oversight, independent observation, and rapid improvement of an immunoassay laboratory at a bioanalytical CRO. This is a hands-on, senior technical role: you will assess current operations and assays, troubleshoot and stabilise critical workflows, mentor bench staff, and deliver concrete, documented process and quality improvements that support timely study delivery in a regulated environment.
This is a temporary, purpose-driven assignment: you will be expected to diagnose key pain points quickly and leave the lab in a measurably stronger position (better protocols, fewer deviations, clearer training, and improved assay performance).

Main Areas of Responsibility

  • Provide technical leadership, mentorship and direct hands-on support for immunoassay workflows (development, validation, sample analysis, troubleshooting).
  • Conduct a rapid technical audit of the immunoassay lab: workflows, SOPs, assay performance, QC/acceptance criteria, equipment, reagent inventory, and staff competencies. Produce a prioritized corrective/improvement plan and present findings to management.
  • Troubleshoot failing assays and analytical variabilities (e.g., high background, matrix effects, poor precision/accuracy) and implement root-cause fixes.
  • Lead assay transfers and re-establish performance for critical assays where needed.
  • Implement or refine process controls, in-process checks, calibration and maintenance routines for key instruments (absorbance readers, MSD, plate washers etc.)
  • Improve data integrity practices and documentation (raw data handling, audit trails, bench notes etc.).
  • Coach and train bench staff on best practices, assay troubleshooting, and assay documentation expectations.
  • Support study timelines by providing senior bench resource when critical assays are high priority.
  • Escalate and communicate risks, status, and mitigation plans to lab management as required.

Qualifications & Experience

Required:

  • Degree in Biology, Biochemistry, Immunology, or related life-science field (BSc minimum; MSc preferred).
  • 8+ years direct hands-on experience developing, validating and running ligand-binding immunoassays (ELISA, MSD or similar) in a regulated bioanalytical environment (CRO/pharma).
  • Demonstrated experience in assay troubleshooting, method transfer, and rapid problem resolution.
  • Practical knowledge of regulatory and quality requirements (GLP, GCP, ISO 17025 or equivalent).
  • Strong data integrity and documentation practice (electronic and paper records).
  • Proven ability to write clear technical reports, SOPs and validation/verification summaries.
  • Excellent interpersonal skills; experience training and mentoring junior staff.
  • Ability to work onsite full-time during the contract period and to start quickly.

Competencies & soft skills

  • Rapid diagnostic thinking - able to triage assays/issues quickly and propose pragmatic fixes.
  • Clear communicator - able to present technical findings to management and clients.
  • Collaborative and coaching orientation - can teach others without creating dependency.
  • Meticulous attention to detail in documentation and data handling.
  • Calm under pressure and focused on delivering measurable outcomes in a compressed timeframe.

PLEASE ENSURE THAT YOUR CV/RESUME IS SUBMITTED IN ENGLISH.

Senior Lab Scientist

Synexa Life Sciences
Macclesfield, UK
Temp, Full-Time

Published on 31/08/2025

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